We are a team of computational and experimental biologists at St. Anna Children's Cancer Research Institute (CCRI). It is our goal to understand developmental processes in cancer biology by employing an integrative approach that combines stem cell biology with functional genomics.

We trace (aberrant) changes in cells during development.

Background: Hematopoiesis, immunity, and cancer
Cell Stem Cell 2016; Science 2016; Cancer Discov. 2019

We map regulatory networks that shape cell identity.

Background: Stem cell transcription factors
Cell Stem Cell 2012, 2013; eLife 2017; EMBO J. 2018

We develop tools that connect pieces of data into knowledge.

Background: Wet- and dry-lab tools and resources
Nat. Methods 2012; Nat. Biotechnol. 2016; Cell Stem Cell 2018

Our research currently focuses on understanding and modulating the earliest effects of cancer-linked mutations on development, tumorigenicity, and plasticity in embryonal tumors and other childhood cancers.

To this end, we use in vitro stem cell and organoid models and genomics technologies. Nat. Commun. 2024


Check out our latest pre-prints and papers: Saldana, Montano, et al., Kirchberger, Shoeb, et al., & Hafemeister & Halbritter


Find out more about our research here! Do you have the know-how, creativity, and passion to join the quest? We'd like to hear from you!


Where to find us:

Developmental Cancer Genomics
Florian Halbritter Lab
St. Anna Children's Cancer Research Institute (CCRI), Zimmermannplatz 10, 1090 Vienna, Austria

On the web:

Other presence of the lab and members.

Our host:

Children's Cancer Research Institute