We are a team of computational biologists at St. Anna Children's Cancer Research Institute (CCRI). It is our goal to understand developmental processes in cancer biology by employing an integrative approach that combines developmental biology with functional genomics.
We trace (aberrant) changes in cells during development.
Now: Using in vitro differentiation to make sense of intra-tumor plasticity
We map regulatory networks that shape cell identity.
Now: Dissecting effects of oncogenic mutations in key regulators
We develop tools that connect pieces of data into knowledge.
Now: Machine learning to translate complex data into simpler components
Check out our most recent pre-prints: Saldana, Montano, et al., Kirchberger, Shoeb, et al., & Hafemeister & Halbritter
Find out more about our research here! Do you have the know-how, creativity, and passion to join the quest? We'd like to hear from you!
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