We are a team of computational biologists at St. Anna Children's Cancer Research Institute (CCRI). It is our goal to understand developmental processes in cancer biology by employing an integrative approach that combines developmental biology with functional genomics.
We trace (aberrant) changes in cells during development.
Now: Using in vitro differentiation to make sense of intra-tumor plasticity
We map regulatory networks that shape cell identity.
Now: Dissecting effects of oncogenic mutations in key regulators